Bioanalysis

Pharmacokinetics and Safety of Intravenous Ferric Pyrophosphate Citrate: Equivalence to Administration via Dialysate

QPS

Pharmacokinetics and Safety of Intravenous Ferric Pyrophosphate Citrate: Equivalence to Administration via Dialysate Read More »

Development and validation of an LC-MS/MS method for simultaneous quantification of co-administered trastuzumab and pertuzumab

QPS

Development and validation of an LC-MS/MS method for simultaneous quantification of co-administered trastuzumab and pertuzumab Read More »

The changing world of bioanalysis: summary of panel discussions

QPS

The changing world of bioanalysis: summary of panel discussions Read More »

Implementing Dried Blood Spot Sampling for Clinical Pharmacokinetic Determinations: Considerations from the IQ Consortium Microsampling Working Group

QPS

Implementing Dried Blood Spot Sampling for Clinical Pharmacokinetic Determinations: Considerations from the IQ Consortium Microsampling Working Group Read More »

Validation of a method for the determination of thiocyanate in human plasma by UV/VIS spectrophotometry and application to a Phase I clinical trial of GDC-0425

QPS

Validation of a method for the determination of thiocyanate in human plasma by UV/VIS spectrophotometry and application to a Phase I clinical trial of GDC-0425 Read More »

In-depth study of homogeneity in DBS using two different techniques: results from the EBF DBS-microsampling consortium

QPS

In-depth study of homogeneity in DBS using two different techniques: results from the EBF DBS-microsampling consortium Read More »

Update of the EBF recommendation for the use of DBS in regulated bioanalysis Integrating the conclusions from the EBF DBS-microsampling consortium

QPS

Update of the EBF recommendation for the use of DBS in regulated bioanalysis Integrating the conclusions from the EBF DBS-microsampling consortium Read More »

The effect of hematocrit on bioanalysis of DBS: results from the EBF DBS-microsampling consortium

QPS

The effect of hematocrit on bioanalysis of DBS: results from the EBF DBS-microsampling consortium Read More »

IS addition in bioanalysis of DBS: results from the EBF DBS-microsampling consortium

QPS

IS addition in bioanalysis of DBS: results from the EBF DBS-microsampling consortium Read More »

Quantification of asenapine and three metabolites in human plasma using liquid chromatography-tandem mass spectrometry with automated solid-phase extraction: application to a phase I clinical trial with asenapine in healthy male subjects

QPS

Quantification of asenapine and three metabolites in human plasma using liquid chromatography-tandem mass spectrometry with automated solid-phase extraction: application to a phase I clinical trial with asenapine in healthy male subjects Read More »

Development and validation of automated SPE-HPLC-MS/MS methods for the quantification of asenapine, a new antiphychotic agent, and its two major metabolites in human urine

QPS

Development and validation of automated SPE-HPLC-MS/MS methods for the quantification of asenapine, a new antiphychotic agent, and its two major metabolites in human urine Read More »

Inductively coupled plasma-MS in drug development: bioanalytical aspects and applications

QPS

Inductively coupled plasma-MS in drug development: bioanalytical aspects and applications Read More »

Recommendations on bioanalytical method stability implications of co-administered and co-formulated drugs by global CRO council for bioanalysis (GCC)

QPS

Recommendations on bioanalytical method stability implications of co-administered and co-formulated drugs by global CRO council for bioanalysis (GCC) Read More »

Bioanalysis of drug in tissue: current status and challenges

QPS

Bioanalysis of drug in tissue: current status and challenges Read More »

Recommendations on: internal standard criteria, stability, incurred sample reanalysis and recent 483s by the global CRO council for bioanalysis

QPS

Recommendations on: internal standard criteria, stability, incurred sample reanalysis and recent 483s by the global CRO council for bioanalysis Read More »

Conference report: the 3rd global CRO council for bioanalysis at the International Reid Bioanalytical Forum

QPS

Conference report: the 3rd global CRO council for bioanalysis at the International Reid Bioanalytical Forum Read More »

High temperature liquid chromatography hyphenated with ESI-MS and ICP-MS for the identification and quantification halogen containing drug metabolites

QPS

High temperature liquid chromatography hyphenated with ESI-MS and ICP-MS for the identification and quantification halogen containing drug metabolites Read More »

Incurred sample accuracy assessment: design of experiments based on standard addition

QPS

Incurred sample accuracy assessment: design of experiments based on standard addition Read More »

Application of dried blood spot sampling combined with LC-MS/MS for genotyping and phenotyping of CYP450 enzymes in healthy volunteers

QPS

Application of dried blood spot sampling combined with LC-MS/MS for genotyping and phenotyping of CYP450 enzymes in healthy volunteers Read More »

Determination of unbound vismodegib (GDC-0449) concentration in human plasma using rapid equilibrium dialysis followed by solid phase extraction and high-performance liquid chromatography coupled to mass spectrometry

QPS

Determination of unbound vismodegib (GDC-0449) concentration in human plasma using rapid equilibrium dialysis followed by solid phase extraction and high-performance liquid chromatography coupled to mass spectrometry Read More »